The closest airports are those of Bari and Brindisi
The railway station is located in Monopoli. Once you get off at your destination, you can take advantage of the shuttle service.
Take the A14 motorway heading south, Bari Nord exit.
Keep driving along the Bari ring road in the direction of Brindisi.
Once in Monopoli, take the Monopoli exit and follow the directions for the city centre